science

2-4 Players
Ages 10+
10-15 minutes

COMPETITIVE

Have you ever dreamed of being an enzyme? Do your thoughts drift to Adenine, Guanine, Thymine and Cytosine more than you’d like to admit? Have you ever wished you could act just like mRNA? Well, you’re in luck!

Linkage is a fast-paced game of DNA transcription… that’s right, DNA transcription!  Players create a shared strand of DNA from a deck of beautifully designed nucleotide cards, and then use their own hand of RNA nucleotides to try to match it.  It’s as easy as protein synthesis!

I know what you’re thinking, “I left my DNA Helicase in my other genome”! It’s OK, you won’t need it with this game!  Gameplay starts with each player drawing 4 cards from the RNA deck, and laying out the DNA promoter next to the DNA deck.  The promoter starts the nucleotide sequence that you will need to try to match to when transcribing your strand. Each subsequent DNA card has a secondary color that corresponds with the color of the RNA nucleotide cards in your hand.

Play starts by laying the first card of the DNA deck next to the promoter, the oldest player then must draw a card and must play a card.  Of course, the goal is to match the laid down DNA card, however, that may not be an option! Once a card is played, the next player completes a draw-play turn.  The turn ends and the next nucleotide is drawn in the DNA strand.

Since RNA transcription is never as simple as it sounds, there are some other mechanics at play.  Chaperone cards act as a wild card and can replace any active nucleotide in your strand, DNA Mutation allows a player to switch out a card in the DNA sequence and any RNA card marked as a Mutation can steal a card from someone else’s RNA strand.

The round continues until the Terminator (no relation to John Connor’s T-800) is drawn.  Players then add up their points for the round, gaining points for each card in the sequence that matches the parent strand, and racking up bonuses for long strands.

Currently, there is no suggested “best play” number of rounds, but our test went well with three.  Playing like a classic card game, Linkage is very much a learning game that puts the entertainment in edutainment. Color matching lends to play with younger kids interested in science, while the more complicated strategic mechanics will keep older kids ribosomes revved up for transcription!

I can’t imagine a better game to teach budding scientists (or even those struggling with the concept of Uracil as a general agent of confusion) some tough concepts through play.  Though many of the mechanics seem advanced, little reading is necessary, as the game can be played via symbol and color recognition.  Children who have mastered games like UNO and Phase 10 might struggle a little with the DNA Mutation and Chaperone cards, but would be able to grasp it after a few rounds of guided play.

Now that the Kickstarter has ended, Linkage has a $19.99 price tag and is available here!